Microdermabrasion is commonly used to treat acne, scarring and other skin irregularities. It is carried out by using an exfoliating material such as crystals or diamond flakes and suction from a microdermabrasion machine.

The exfoliating material is pumped at pressure towards the skin, causing abrasion, while the vacuum removes the crystal material and exfoliated skin cells. Microdermbarasion helps to exfoliate or temporarily remove a few of the top layers of the skin (the stratum corneum).

Dermoelectroporation is a type of transdermal skin therapy. It is commonly used as an alternative route of administration for water soluble drug solutions, as opposed to traditional injections. 

The device delivers a controlled electric current to the skin, opening water channels to which ionised drug solution is administered, and then absorbed by the skin. The most popular medical laser machines used for this treatment are the Mattioli DEP and Ultrapeel.